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Author: Brian S McGowan, PhD

MANUSCRIPT: An overview of the design and methods for retrieving high-quality studies for clinical care.

Abstract
BACKGROUND:
With the information explosion, the retrieval of the best clinical evidence from large, general purpose, bibliographic databases such as MEDLINE can be difficult. Both researchers conducting systematic reviews and clinicians faced with a patient care question are confronted with the daunting task of searching for the best medical literature in electronic databases. Many have advocated the use of search filters or “hedges” to assist with the searching process. The purpose of this report is to describe the design and methods of a study that set out to develop optimal search strategies for retrieving sound clinical studies of health disorders in large electronics databases.
OBJECTIVE:
To describe the design and methods of a study that set out to develop optimal search strategies for retrieving sound clinical studies of health disorders in large electronic databases.
DESIGN:
An analytic survey comparing hand searches of 170 journals in the year 2000 with retrievals from MEDLINE, EMBASE, CINAHL, and PsycINFO for candidate search terms and combinations. The sensitivity, specificity, precision, and accuracy of unique search terms and combinations of search terms were calculated.
CONCLUSION:
A study design modeled after a diagnostic testing procedure with a gold standard (the hand search of the literature) and a test (the search terms) is an effective way of developing, testing, and validating search strategies for use in large electronic databases.

via An overview of the design and metho… [BMC Med Inform Decis Mak. 2005] – PubMed – NCBI.

ABSTRACT: Standardization of search methods for guideline development: an international survey of evidence-based guideline development groups

Abstract
BACKGROUND:
Effective literature searching is particularly important for clinical practice guideline development. Sophisticated searching and filtering mechanisms are needed to help ensure that all relevant research is reviewed.
PURPOSE:
To assess the methods used for the selection of evidence for guideline development by evidence-based guideline development organizations.
METHODS:
A semistructured questionnaire assessing the databases, search filters and evaluation methods used for literature retrieval was distributed to eight major organizations involved in evidence-based guideline development.
RESULTS:
All of the organizations used search filters as part of guideline development. The medline database was the primary source accessed for literature retrieval. The OVID or SilverPlatter interfaces were used in preference to the freely accessed PubMed interface. The Cochrane Library, embase, cinahl and psycinfo databases were also frequently used by the organizations. All organizations reported the intention to improve and validate their filters for finding literature specifically relevant for guidelines.
DISCUSSION:
In the first international survey of its kind, eight major guideline development organizations indicated a strong interest in identifying, improving and standardizing search filters to improve guideline development. It is to be hoped that this will result in the standardization of, and open access to, search filters, an improvement in literature searching outcomes and greater collaboration among guideline development organizations.

via Standardization of search methods for gui… [Health Info Libr J. 2008] – PubMed – NCBI.

ABSTRACT: When is a search not a search? A comparison of searching the AMED complementary health database via EBSCOhost, OVID and DIALOG.

Abstract
BACKGROUND:
The researchers involved in this study work at Exeter Health library and at the Complementary Medicine Unit, Peninsula School of Medicine and Dentistry (PCMD). Within this collaborative environment it is possible to access the electronic resources of three institutions. This includes access to AMED and other databases using different interfaces.
OBJECTIVES:
The aim of this study was to investigate whether searching different interfaces to the AMED allied health and complementary medicine database produced the same results when using identical search terms.
METHODS:
The following Internet-based AMED interfaces were searched: DIALOG DataStar; EBSCOhost and OVID SP_UI01.00.02. Search results from all three databases were saved in an endnote database to facilitate analysis. A checklist was also compiled comparing interface features.
RESULTS:
In our initial search, DIALOG returned 29 hits, OVID 14 and Ebsco 8. If we assume that DIALOG returned 100% of potential hits, OVID initially returned only 48% of hits and EBSCOhost only 28%. In our search, a researcher using the Ebsco interface to carry out a simple search on AMED would miss over 70% of possible search hits. Subsequent EBSCOhost searches on different subjects failed to find between 21 and 86% of the hits retrieved using the same keywords via DIALOG DataStar. In two cases, the simple EBSCOhost search failed to find any of the results found via DIALOG DataStar.
CONCLUSIONS:
Depending on the interface, the number of hits retrieved from the same database with the same simple search can vary dramatically. Some simple searches fail to retrieve a substantial percentage of citations. This may result in an uninformed literature review, research funding application or treatment intervention. In addition to ensuring that keywords, spelling and medical subject headings (MeSH) accurately reflect the nature of the search, database users should include wildcards and truncation and adapt their search strategy substantially to retrieve the maximum number of appropriate citations possible. Librarians should be aware of these differences when making purchasing decisions, carrying out literature searches and planning user education.

via When is a search not a search? A comparis… [Health Info Libr J. 2009] – PubMed – NCBI.

ABSTRACT: The impact of information skills training on independent literature searching activity and requests for mediated literature searches.

Abstract
BACKGROUND:
Most NHS library services routinely offer both mediated searches and information skills training sessions to their users. We analyse the impact of these two services on the amount of literature searching demonstrated by users of hospital- based library services in the north-west of England.
METHODS:
Data for (1) mediated literature searches, (2) number of library users attending information skills training sessions, (3) amount of library staff time devoted to information skills training, and (4) number of Athens-authenticated log-ins to databases were obtained from statistical returns for 2007, and analysed for significant correlations.
RESULTS:
There was evidence of quite strong correlations between the two measures of training activity and the number of mediated literature searches performed by library staff. There was weaker evidence of correlation between training activity and total literature searching activity.
DISCUSSION:
Attending training sessions may make some library users aware of the difficulty of complex literature searches and actually reduce their confidence to perform their own complex searches independently. The relationships between information skills training, mediated literature searches, and independent literature searching activity remain complex.

via The impact of information skills training… [Health Info Libr J. 2010] – PubMed – NCBI.

MANUSCRIPT: Knowledge transfer in surgery: skills, process and evaluation.

Abstract
INTRODUCTION:
Knowledge transfer is an essential element in the management of surgical health care. In a routine clinical practice, surgeons need to make changes to the health care they provide as new clinical evidence emerges.
MATERIALS AND METHODS:
The information was derived from the authors’ experience and research in evidence-based practice, searching of the literature, teaching and organisation of various national and international workshops on evidence-based medicine.
DISCUSSION:
This manuscript discusses principles of knowledge transfer in surgery including evaluation of recommended changes that can improve quality of health care in routine surgical practice. Skills, process and evaluation are carefully described. Continuous information delivery is required to enable surgeons to improve knowledge transfer and to keep up to date their knowledge.

via Knowledge transfer in surgery: skills, … [Ann R Coll Surg Engl. 2007] – PubMed – NCBI.

ABSTRACT: Enhancing retrieval of best evidence for health care from bibliographic databases: calibration of the hand search of the literature.

Abstract
BACKGROUND:
Medical practitioners have unmet information needs. Health care research dissemination suffers from both “supply” and “demand” problems. One possible solution is to develop methodologic search filters (“hedges”) to improve the retrieval of clinically relevant and scientifically sound study reports from bibliographic databases. To develop and test such filters a hand search of the literature was required to determine directly which articles should be retrieved, and which not retrieved.
OBJECTIVE:
To determine the extent to which 6 research associates can agree on the classification of articles according to explicit research criteria when hand searching the literature.
DESIGN:
Blinded, inter-rater reliability study.
SETTING:
Health Information Research Unit, McMaster University, Hamilton, Ontario, Canada. Participants: 6 research associates with extensive training and experience in research methods for health care research. Main outcome measure: Inter-rater reliability measured using the kappa statistic for multiple raters.
RESULTS:
After one year of intensive calibration exercises research staff were able to attain a level of agreement at least 80% greater than that expected by chance (kappa statistic) for all classes of articles.
CONCLUSION:
With extensive training multiple raters are able to attain a high level of agreement when classifying articles in a hand search of the literature.

via Enhancing retrieval of best evide… [Stud Health Technol Inform. 2001] – PubMed – NCBI.

MANUSCRIPT: The effect of training on question formulation among public health practitioners: results from a randomized controlled trial.

Abstract
OBJECTIVE:
To improve understanding of the information-seeking behaviors of public health professionals, the authors conducted this randomized controlled trial involving sixty participants to determine whether library and informatics training, with an emphasis on PubMed searching skills, increased the frequency and sophistication of participants’ practice-related questions.
METHODS:
The intervention group (n = 34) received evidence-based public health library and informatics training first, whereas the control group (n = 26) received identical training two weeks later. The frequency and sophistication of the questions generated by both intervention and control groups during the interim two-week period served as the basis for comparison.
RESULTS:
The intervention group reported an average of almost 1.8 times more questions than those reported by the control group (1.24 vs. 0.69 questions per participant); however, this difference did not reach statistical significance. The intervention group overall produced more sophisticated (foreground) questions than the control group (18 vs. 9); however, this difference also did not reach statistical significance.
CONCLUSION:
The training provided in the current study seemed to prompt public health practitioners to identify and articulate questions more often. Training appears to create the necessary precondition for increased information-seeking behavior among public health professionals.

via The effect of training on question formulat… [J Med Libr Assoc. 2008] – PubMed – NCBI.

ABSTRACT: Errors in search strategies were identified by type and frequency.

Abstract
OBJECTIVE:
Errors in the electronic search strategy of a systematic review may undermine the integrity of the evidence base used in the review. We studied the frequency and types of errors in reviews published by the Cochrane Collaboration.
STUDY DESIGN AND SETTING:
Data sources were MEDLINE searches from reviews in the Cochrane Library, Issue 3, 2002. To be eligible, systematic reviews must have been of randomized or quasi-randomized controlled trials, reported included and excluded studies, and used one or more sections of the Cochrane Collaboration’s Highly Sensitive Search Strategy. MEDLINE search strategies not reported in enough detail to be assessed or that were duplicates of a search strategy already assessed for the study were excluded. Two librarians assessed eligibility and scored the eligible electronic search strategies for 11 possible errors. Dual review with consensus was used.
RESULTS:
Of 105 MEDLINE search strategies examined, 63 were assessed; 31 were excluded because they were inadequately reported, and 11 were duplicates of assessed search strategies. Most (90.5%) of the assessed search strategies contained > or =1 errors (median 2, interquartile range [IQR] 1.0-3.0). Errors that could potentially lower recall of relevant studies were found in 82.5% (median 1, IQR 1.0-2.0) and inconsequential errors (to the evidence base) were found in 60.3% (median 1, IQR 0.0-1.0) of the search strategies. The most common search errors were missed MeSH terms (44.4%), unwarranted explosion of MeSH terms (38.1%), and irrelevant MeSH or free text terms (28.6%). Missed spelling variants, combining MeSH and free text terms in the same line, and failure to tailor the search strategy for other databases occurred with equal frequency (20.6%). Logical operator error occurred in 19.0% of searches.
CONCLUSION:
When the MEDLINE search strategy used in a systematic review is reported in enough detail to allow assessment, errors are commonly revealed. Additional peer review steps are needed to ensure search quality and freedom from errors.

via Errors in search strategies were identified… [J Clin Epidemiol. 2006] – PubMed – NCBI.

MANUSCRIPT: A survey of the use of electronic scientific information resources among medical and dental students.

Abstract
BACKGROUND:
To evaluate medical and dental students’ utilization of electronic information resources.
METHODS:
A web survey sent to 837 students (49.9% responded).
RESULTS:
Twenty-four per cent of medical students and nineteen per cent of dental students searched MEDLINE 2+ times/month for study purposes, and thiry-two per cent and twenty-four per cent respectively for research. Full-text articles were used 2+ times/month by thirty-three per cent of medical and ten per cent of dental students. Twelve per cent of respondents never utilized either MEDLINE or full-text articles. In multivariate models, the information-searching skills among students were significantly associated with use of MEDLINE and full-text articles.
CONCLUSION:
Use of electronic resources differs among students. Forty percent were non-users of full-text articles. Information-searching skills are correlated with the use of electronic resources, but the level of basic PC skills plays not a major role in using these resources. The student data shows that adequate training in information-searching skills will increase the use of electronic information resources.

via A survey of the use of electronic scientific in… [BMC Med Educ. 2006] – PubMed – NCBI.

MANUSCRIPT: Searching bibliographic databases for literature on chronic disease and work participation.

Abstract
BACKGROUND:
The work participation of people with chronic diseases is a growing concern within the field of occupational medicine. Information on this topic is dispersed across a variety of data sources, making it difficult for health professionals to find relevant studies for literature reviews and guidelines.
AIM:
The goal of this project was to identify bibliographic databases and search terms that could be most useful for retrieving relevant studies on this topic.
METHODS:
Five broad questions regarding work participation and chronic disease were formulated, focusing on angina pectoris, depression, diabetes mellitus, hearing impairment and rheumatoid arthritis. A search strategy for retrieving information on these questions was developed and run in five bibliographic databases: Medline, EMBASE, PsycINFO, Cinahl and OSHROM. Relevant publications were selected from the search results. The utility of the selected databases and search terms was evaluated by analysing the number of relevant publications that were retrieved.
RESULTS:
The number of relevant publications retrieved from each database varied. Most (84%) of the relevant publications that were retrieved from each database were unique to that source. For each database, specific search terms for the concept of ‘work’ were useful for retrieving relevant publications.
CONCLUSION:
Medline, EMBASE and PsycINFO are useful databases for quick searches. Useful search terms for the concept of ‘work’ are work capacity, work disability, vocational rehabilitation, occupational health, sick leave, absenteeism, return to work, retirement, employment status and work status. For comprehensive searches, we recommend additional searches in Cinahl and OSHROM, adapting the search terms to specific databases

via Searching bibliographic databases for liter… [Occup Med (Lond). 2006] – PubMed – NCBI.