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Tag : leading indicators

The Earliest Warning Sign: How Measuring Readiness at Training Predicts Trial Risk Before It Shows Up in the Data

Most protocol deviations start as human problems, not operational ones, but risk-based monitoring typically relies on lagging indicators that arrive too late to prevent these problems instead of measuring readiness during training, when intervention still matters. This article was first posted March 11, 2026 in Applied Clinical Trials Volume 35, Issue 2: 4-01-2026 “Readiness, measured during